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RE: Oncology Xenograft Models: Using mice to test cancer treatments
What's the relation of hair and immunosupression? The first successful immunosuppressed mice just happened to be nude?
cells may not grow depending on the type of cancer and the strain of mouse
Didn't know cancer could be so fussy!
I'm not quite sure. The mutation that leads to this strain of mice inhibits the development of the Thymus which is responsible for T cell production. Maybe the thymus is also necessary for hair growth?
It's also possible that the mutation affects a basic developmental pathway influcencing multiple aspects of development and the two most noticeable phenotypes are hair loss and immunosupression.