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RE: What's up with nucleases?
Ah, I think I said "nucleobases" in my "Building blocks of life" post and didn't want to confuse people, so I stuck with it. But you're right, it's not completely correct.
Ofc I see this comment after inviting you to the discord server ^^
The topic of my thesis is basically that I try to combine CRISPR/Cas9 with Cre/loxP for more efficient gene knock-in.
If it works out that would really be great! I'm really excited to see where this tech is in five years. I think it's going to be integral in fixing so many diseases and disabilities! It's definitely going to be the greatest medical breakthrough in the 21st century so far once it is fully realized! Good luck on your thesis!