Your gut microbiome can convert A and B blood types into the universal type O

in #steemstem6 years ago (edited)

Your gut microbiome can convert A and B blood types into the universal type O.


Source
CC0 Creative Commons

Another fascinating thing our gut bacteria do...

Within the ABO blood group system, you are either type A, B, AB or O depending on the nature of the antigen present on your red blood cells.

Recently at the National Meeting & Exposition of the American Chemical Society (1) researches presented work that show they have identified enzymes from the human gut microbiome that can convert type A or B blood into type O. The enzymes recognize and cleave the A and B antigens on red blood cells (simple sugars).

The researchers hope that one day these enzymes could be used to convert type A or B blood into universal donor Type O blood in emergency situations. Type O blood donors are universal donors because their blood does not have the A or B antigens and when given to a recipient it will not be seen as a foreign antigen and therefore not cause a immune response.

The research was done at the University of British Columbia Canada, headed by professor Stephen Withers.

Sources:
(1 )Withers S et al. Discovery of CAZYmes for cell surface glycan removal through metagenomics: towards universal blood. Presented at: the 256th National Meeting & Exposition of the American Chemical Society, Boston, MA, USA, 19–23
Link to the abstract

You can watch a YouTube video of the research here:

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Hey rcebike,

could this be dangerous for humans somehow. For instance by changing the whole blood type. I never heard things like this before. But the imagination is somehow creepy.

Best regards

Hey @chappertron
sorry for the late reply as I was away up north for a week without internet. I don't think the gut bacteria will change the blood type of the person per se but the researchers want to utilize the the enzymes produced by these bacteria to convert A or B blood to O and then use this converted blood as donor blood.
cheers!

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