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Amazing article. You really put much effort in it and it is extremely good. Good work buddy! Cheers!

Thanks! I still don't feel like even scratching the surface... But I'm glad you liked it :)

This is the same reason why drinking Grapefruit juice with coffee can increase the effects of caffeine, right? It slows down the liver processing it.

Well, as I said. It's a pretty complex topic so I'll try to answer your question as good as possible with links related to current research.

While caffeine is generally metabolized by a one specific Enzyme of this CYP P450 family (CYP 1A2 to be exact), Naringin mostly inhibits CYP3A4, which belongs to the same Enzyme-system but is part of another subfamily. Thus the effect of your coffee should probably not be significantly increased.

I just searched for some studies who were looking into this and found this.

Feel free to take a look into it.

General description of caffein including the metabolizing enzyme
Studies researching a possible interaction 1 + 2
Studies about the pharmakokinetics of grapefruit juice including some drugs it might interact with (This is not a complete list.) 1 + 2
Don't think every other medicine is save to combine with grapefruit juice. The best thing to drink when you're taking medicine still is simple water.

All in all I doesn't seem like combining grapefruit juice with coffee seems to have a significant impact on the caffein in your blood.

It's like the extra robots are chasing some of your IT-specialists that are mainly experts for one OS but leaving the other ones who are responsible for the "caffeine"-bots' OS do their work in peace.

Haha haven't seen that yet.
Hope you still enjoyed the read and maybe even learned something new (even though I guess you're probably learning this in biochemistry during your medicine studies)

Thanks for the feedback! :)

you are welcome!
you may read it if you like! thanks

This post was upvoted by 15% from Operation Support sponsored with Whaleshares and BeyondBit !

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