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RE: Diabetes, Fasting Glucose Analysis, And How Likely Am I To Die Anyway?
Young Vs. Old Hazard Ratio -
Age related increase in fasting blood glucose tapers off substantially so naturally the hazard ratio should plateau with respect to that
also general thoughts -
diabetes is best solved by addressing insulin resistance - https://intensivedietarymanagement.com/failure-blood-glucose-paradigm/
The issue is that drug companies use this research as supporting evidence that you should medicate with low efficacy to "manage" it in the short term when in the long term you aren't helping yourself if you don't address the root problems inflating the numbers.
This is a good thought, but not why. Think about what a hazard ratio is a ratio of. What changes with age?
I guess the other thought would be if you are in the red young in life, so to speak, your long term risk is substantially higher...i.e early coronary heart disease/atherosclerosis?
This is basically the reason. Your risk of mortality is lower when you are younger so the denominator is small. Increased risk for the changing variable leads to a much bigger hazard ratio. When you get older your overall risk of mortality is much higher so the difference between the two is smaller, this a smaller hazard ratio.
So, that is the reason.....Is there anything like "difference in tolerance of body to high Blood Glucose level with increasing age", ..do young people have low tolerance to high blood glucose than the old people?.....that may also affect the hazard ratio....searched but could not found about it...
Younger people having a lower tolerance to higher glucose? It's a good question, would have to do a literature search to find if anything is available. We're that observed it may also contribute.
You can take me, but you cannot take my bunghole.... For I have no bunghole....