At this point it is not possible to edit the genome of a whole individual with Cas9, it is very very difficult to deliver the protein to enough cells. Without a delivery mechanism then editing on a large scale is not possible.

The issue is alleviated when editing in an freshly fertilized embryo as there is only one, or a limited number of cells. Cas9 and a respective guide crRNA can be delivered directly to the cell to cut where it is wanted in that case. However for an adult, there are just so many cells, even in a particular organ there are a very large number of cells. Editing on this sort of scope is not possible to date.