Not particularly. With GMO's people are usually concerned with the proteins that are artificially expressed, or the changes that are induced to natural protein expression states. IMO those concerns are valid in some cases, and silly in others (its all dependent on exactly what aspect of the organism was changed). I don't think I have read anyone discussing concerns over the DNA itself, however knowing that our bodies really don't seem to uptake any of the foreign DNA would certainly be good to present to someone who did have such a concern. As any editing to the DNA wouldn't really matter (with regards to our health) because its not being taken in to begin with.