I agree that bio engineering is both a blessing and a curse. Modern biotech labs work with some really crazy stuff and even though they have extensive countermeasures in place to prevent some GE monster from getting out it doesn’t mean that it won’t.

I think a terminator / skynet or matrix type scenario is more likely to kill off most of mankind within our lifetimes but genetic engineering is also a likely candidate to spawn something that could wipe us all out.