Should we continue to explore the issue of post-vaccination syndrome, even if we can't give a definitive answer to whether it is caused by COVID-19 vaccines?

For context, this is a question I answered on Quora

We may not have a definitive answer about the cause but we do have a preponderance of evidence that the modRNA lipids and translated spike protein is itself a toxin and can cause damage to various organs depending on where the lipids are distributed throughout the body.

The spike protein is pathogenic from both the vaxx and the virus:

See: ‘Spikeopathy’: COVID-19 Spike Protein Is Pathogenic, from Both Virus and Vaccine mRNA

This narrative review presents two possible mechanism by modRNA translated spike:

1. Accumulation in cells results in programmed cell death.
2. The receptor binding domain has a toxin-like binding domain.

Circulating Spike Detected Up to 709 days after the Vaxx in Post Vaxx Syndrome Patients

A cross sectional case control study of patients suffering from post vaxx syndrome with no pre-existing comorbidities who were compared with vaxxed healthy controls (n = 64) found, through peripheral blood mononuclear cells, distinct immune signatures between cases (n = 42) and controls (n = 22) with the former having a significantly lower percentage of type 2 dendritic cells, type 1 and 2 T helper cells, and a higher proportion of non-classic monocytes. The cases had a significantly higher proportion of exhausted cytotoxic T cells and exhausted helper T cells compared to controls with a significantly higher level of tumor necrosis factor cytokine levels. A separate assessment found that cases had significantly higher antibodies against glycoprotein-42 of the Epstein-Barr Virus and greater reactivity to peptides of glycoprotein-42 and 350 than controls indicating Epstein-Barr Virus reactivation in vaxx injured patients. Subgroup analysis revealed no difference in this reactivity between cases with prior SARS-COV-2 infections (n = 15) and cases with no prior infection (n = 27). Participants with post vaxx syndrome both with and without prior infection had significantly higher detectable circulating Spike Subunit 1 than controls without infection between 26 (nearly a month) and 709 days (nearly 2 years) after the vaxx. Compared to an external control group with and without prior infection, included in a long COVID study conducted at Mount Sinai clinics (n = 134), post vaxx syndrome patients in this study ‘demonstrated significantly higher S1 (spike subunit 1) levels in circulation. Another assessment found that ‘individuals with post vaxx syndrome exhibited elevated levels of circulating full-length Spike compared to healthy controls. A subgroup analysis of the post vaxx syndrome group revealed that the subgroup without prior infection had the highest levels of detectable S1 subunit the furthest away from their immunizing event ranging from 600-700 days. Most participants in the prior infection subgroup (25/27) experienced infection after immunization ‘indicating that post vaxx syndrome symptoms started prior to infection.’ Post vaxx syndrome patients without prior infection were also found to have elevated growth hormone levels and low thyroid stimulating hormone levels compared to others groups.

This is not the first study to falsify the marketing claims that the modRNA lipids and spike protein are cleared from the body within a few days or within a week and stay at the injection site. There are about 2 dozen at this point which I have summarized in a three part series:

Spike Protein Detected in Vaccinated Blood Well After A few Days (Part 1)

(Part 2)

(Part 3)

Experimental Evidence Vaxx Spike Protein is a Cardiotoxin

As I mentioned last year in a prior post, a study involving 3 experiments conducted with rodents, human cell culture and rodent Langendorff hearts modRNA lipids and translated spike protein were demonstrated to be a cardiotoxin that cause stress induced cardiomyopathy. An autopsy study of two teenage boys who died shortly after receiving their second modRNA doses supported these findings.

We also have a ton of observational evidence from adverse event reports around the world. Although observational evidence is a lower standard of evidence than experimental evidence it still adds weight to the theory. Of course, these are a dime a dozen and too numerous to fit into one answer with Quora’s character limits so I’ll just provide the most recent examples:

Acute Transverse Myeltis Increases after COVID Vaxx

A nationwide population based self-controlled case series study conducted in the Republic of Korea using data from the Korea Disease Control and Prevention Agency on all 42 million vaxxed adults and data from the National Health Insurance claims database for diagnosed cases of acute transverse myelitis occurring within at least 42 days of the first dose over a 270 day observation period following subsequent doses ending in August 2022, found that the COVID vaxx increased the risk of incident rate of acute transverse myelitis almost 2.5x higher than baseline risk. This was consistent across different COVID vaxx platforms and demographics.

ModRNA transfection Renal Injury 13x more common than global background rate.

A global pharmacovigilance study that analyzed renal adverse events reported after administration of 19 different immunizations and recorded in the WHO VigiBase between 1967 and 2022 found that modRNA transfections had the highest proportion of three types of kidney related injuries (acute kidney injury, inflammation of glomeruli, and inflammation of tubules) after 2020. Recipients of modRNA transfections reported inflammation of glomeruli after administration at more than 13x the rate of any of other immunizations and acute kidney injury plus inflammation of tubules at more than 2x the rate of any other immunization in the database with 25% suffering serious outcomes resulting in post sequelae or death. The surge in renal vaxx injuries after 2020 was disproportionately concentrated among adolescents between 12 and 17 years of age, which as I noted in previous posts is the highest risk age group from vaxxed induced myocarditis and pericarditis as well.

Pregnancy risks

A retrospective, population-based cohort study that queried the VAERS database between 1990 and 2024 for 37 different pregnancy complications, including 27 before birth and 10 after birth, found that compared to all other immunizations, those associated with COVID-19 had a proportional reporting ratio greater than 2 across all 37 adverse events with a mean proportional reporting ratio of 69.3.

Other post immunization Disorders

A retrospective cohort study conducted in India between the beginning of April and end of December 2021 among vaxxed patients admitted to the ICU for non-COVID-19 illnesses after their last dose across 4 centers (n = 175) found that median time from vaccination to ICU admission was 55 days (< 8 weeks) and the range of non-COVID-19 illnesses included neuromuscular illness such as Guillian Barre syndrome (n = 6) and thromboembolic (blood clots) events (n = 28) and about a quarter of them died in ICU.