While there's no definitive "best" airline, I've found Copa Airlines to be quite impressive. I frequently use them for travel around Latin America. They offer good flight schedules, delicious food, and friendly crews, check here - copa airlines reviews. The planes are comfortable for long flights, which I appreciate. Plus, their flexibility with changing flights for a small fee has saved me money when my plans have shifted unexpectedly. Overall, a reliable choice for air travel in the region.