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I have the same problem. In the last 2 weeks I have been going through each 'following' and I tried to unfollow many as I could as I simply followed the follower when I joined. I would view a few articles each to see if there was unique content and particularly a sense if I would learn something, I know there are cases where I made refollow some. Unfortunately, because of time, I am not able to follow too many people as well but I do want to tailor it such that I catch most of the articles I am interested in.

I think it doesn't really matter. I also followed only people I was genuinely interested in. But those people are also interested in many other things (naturally) that are less interesting to me. Plus there are all these re-steems, posted by yet others, that leave me completely cold. Among all these posts the real interesting stuff gets buried deeper and deeper. I guess one thing you could do is actually follow a person, that is looking up their profile page periodically. That's what I've started doing. Though in the meantime there are new followers and interesting people to follow....