As for handling it, the same wiki states:

''Although evidence suggests that wheel bugs can seemingly be domesticated in controlled environments, if provoked or mishandled, they may attack in an act of defense. As a cautionary warning, the bite of a wheel bug is generally considered to be of greater severity in terms of the level and duration of pain than the sting of common insects like wasps. The resulting wound is documented to be extremely painful, lasting, and lingering, accompanied by an unceasing numbness which can persist for days. ''