Nice article.
I like Wilde's quote that moderation should be in moderation. I work in finance in NYC and I rub shoulders with people who have climbed to the top of the industry while making close to a million at a very young age. I would say that, by and large, these people have taken everything in moderation.
Moderation doesn't mean never experimenting and never getting in trouble. It's having a variety of experiences, risky and safe ones. When I see people that have gone over the edge from their excesses, they're famous only because their drama catches people's attention, not because they did anything particularly great.
Doing everything, literally, in moderation isn't really moderation now is it?