The most outstanding idiocy of this serotonin-centric antidepressant 'research' is that right next to it is also this 'dopamine theory' of addiction. Depression is lack of motivation, essentially. Addiction is acute motivation towards a specific activity. In fact, dopamine-agonists and reuptake inhibitors are far more effective at temporarily diminishing depression, thus the comment about alcohol. Alcohol does not directly raise dopamine, but rather it attenuates GABA activity and this causes a temporary rise in the activity of one of gaba's opposing neurotransmitters, being dopamine (and norepinephrine of course).

In fact, the absolute best antidepressant, and it's very hard to get your hands on it, is a russian developed peptide drug called Semax. This is a 7 unit amino acid peptide chain containing a fragment of a spleen enzyme. This peptide causes an increase of activity of astrocytes and physically causes the hippocampus to grow in size. The way this fights depression is actually by dramatically increasing neuroplasticity and neuroplasticity is what is required to learn. So in fact depression is simply giving up on learning. Addiction really is another version of this that is active rather than passive.