I was curious also. When that happens just watch the research happen!
I found a lot of information that was very detailed about the medicinal (both traditional and more recent) uses and the chemical reasoning behind it at 2beingfit.com but there were some warnings too.

Some sites (eg. Webmed.com, and drugs.com) advise not to take a supplement that contains bitter orange (where it is a concentrated product) or to drink the juice if you are already using a stimulant such as caffeine or decongestants or are taking blood pressure meds as it has been linked to heart probs.

I guess it just shows the importance of your decisions in what you eat. If it can make that much difficulty in your health issues then things like this also have potential for great benefits!

The 2beingfit site also has similar info on other common fruits including the fig, which Papa-Pepper has already covered in this series!