Introduction

I'm writing to share my daily activity with you in school today.

class board

We just did some revisions today together preparing for our National exam from CHBPRN for licensing us as community health extension workers

We are there in the community where and when there's no doctor dealing with some diseases or ailments of plaguing the community.
We're there to render preventive, promotive, rehabilitation and curative health services to the communit within the scope of our standing order.
Today I'll tell you a brief presentation I made in the class about the pathogenesis if sickle cell.

the selfie in my professional outfit waiting for my coursemates to come before presenting my study
Before I start, let's define some medical terms in a lay man understanding.
These terms are pathogenesis, pathophysiology, physiological disease, pathogenic diseases, hereditary and deficiency disease.
Knowing these terms will help us to group sickle cell disease.
Let's start now 👇

What's pathogenesis

This can be defined as the origination and development of a disease.
The beginning of the disease manifestation, the process of it's manifestation and the effect of it's manifestation.
The stages of the disease development is called pathogenesis.

What's the pathophysiology

This is the study of physical and biological abnormalities occuring within the body as the result of the disease.
Simply put, it is the deformation in the function of body's structure structure due to a disease and the concormitants of disease process.

Classification of diseases.

Diseases are classified in to the following group.

• Physiological disease
• pathogenic disease
• Hereditary disease
• Deficiency disease

physiological disease.

Physiological disease are those diseases or disorders that interferes with function of the body system and can be genetic or hereditary.
Your body's anatomical function doesn't work and act as put by the creator.
For example, if the insulin released by the pancreas can no longer act on the glucose or sugar which results to the sugar entering into blood and urine this means that there's impairment in the function of insulin and may lead to Diabetes milletus 2.
Or the pancreas in the body can't release insulin to work on those Glucose to store as glycogen in the body which results to Diabetes milletus 1.
These two cases above is physiological.
If the haemoglobin which is the pigment of the red blood cells is defective due to some genetic deformation and could not produce healthy cone shaped cells but sickle shaped cells which is known as sickle cell Anaemia, the sickle shaped cells prevent the blood vessels to carry out oxygen to the body leading to crisis.
This is physiological because there's malfunction in the body's system.

pathogenic disease

This is the disease caused by the manifestation and involvement of a pathogen.
A pathogen is a disease causing organisms. They're aetiological.
Whenever there's a communication or relationship of one's disease associated with an organism, be it bacterial, fungal, viral, nematidal, helminths, protozoan and plasmodium. the disease is pathogenic and pathological.
Pathogenic disease is communicable.
Example is malaria.
Malaria is associated with the manifestation of plasmodium. The vector of this pathogen is female anepheles mosquitoes.

Hereditary or genetic disease.

These are the diseases that one inherited from his parents due to the mutation of genes or genes deformation. Or the transfer of some genetic traits to the offspring by the parents.
Example is sickle cell Anaemia.

Deficiency disease

This disease is caused by the the lack of a nutrient, elements and vitamins in the body.
Example is scurvy, marasmus.

Sickle cell Anaemia

Sickle cell Anaemia is the physiological disorder in which the haemoglobin of the red blood cells is defective due to inherited Gene malformation and prevents the blood to carry out oxygen to the body.
Naturally, the haemoglobin move easily through blood vessels due to its flexibility and come shaped formation.

source

In sickle cell anaemic patient, the haemoglobin is flawed and shaped like sickles and can be rigid and sticky enough to get stuck in blood vessels which can slow down the blood flow and oxygen to parts if the body.
With these empirical study, I propose that sickle cell Anaemia is physiological and hereditary.

The pathophysiology of sickle cell Anaemia

This is the mutation in the beta globin genes which leads to the substitution of valine for glutamic acid.
This leads to the deoxygenation where the mutated haemoglobin molecules combine to form bundles.

Conclusion

After my presentation, we took some test.
We took about four courses today. My brain is already depreciating.
Right now, I'm about to read my books for tomorrow's exams.
We're starting our semi finals from tomorrow.
I came back home.
I was very tired. I had to cook rice and egg sauce tomatoes.

my brunch

Cheers @whitestallion, @focusnow