Downstream Processing Market: Key Trends and Innovations Shaping the Industry
The global downstream processing market is experiencing significant growth, valued at USD 30.96 billion in 2022 and projected to expand at a CAGR of 14.84% from 2023 to 2030. A key driver of this growth is the increased utilization of downstream processing techniques for developing COVID-19 vaccines.
Recent industry collaborations further highlight the market's momentum. In March 2022, Rentschler Biopharma and Vetter launched the Xpert Alliance, a strategic partnership aimed at providing innovative solutions to meet the evolving demands of the biopharmaceutical industry.
Additionally, in April 2022, Bayer announced its intention to collaborate with Ginkgo Bioworks, involving the sale of Bayer's West Sacramento Biologics R&D location and internal discovery platform. This strategic move positions Bayer to strengthen its leadership in biologics, access advanced synthetic biology technologies, and solidify its position as a preferred partner for biologics research, development, and commercialization.
Gather more insights about the market drivers, restrains and growth of the Downstream Processing Market
Technique Segmentation Insights
Purification by Chromatography
Chromatography-based purification dominated the downstream processing market in 2022, capturing a significant 40.98% revenue share. Single-use chromatography and filtration systems are widely recognized as industry standards in bioprocessing. To strengthen their market position, companies are actively pursuing strategies like acquisitions, mergers, and partnerships to expand their chromatography portfolios.
For example, Repligen's acquisition of BioFlex Solutions in 2021 enhanced its single-use fluid management product line and streamlined its supply chain. Similarly, Danaher Corporation's acquisition of Aldevron in 2021 bolstered its Life Sciences sector's capabilities.
Solid-Liquid Separation
Solid-liquid separation is projected to experience the highest CAGR of 16.03% from 2023 to 2030. This technique offers several advantages, including simplicity, cost-effectiveness, and suitability for continuous manufacturing. However, it can generate high shear forces, which can be problematic.
To address this challenge, recent advancements like multistage depth filtration, alternating tangential flow microfiltration, and tangential flow filtration are gaining popularity, especially for high cell density processes.
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