Yes, it is possible to make an AI application running on blockchain. For example, AI on blockchain can be used to create a predictive market, whereby data and algorithms are used to predict future events such as stock prices, sports outcomes, commodity prices, or any other type of event. Such applications would be powered by a combination of distributed ledger technology, AI models, and smart contracts. The AI models would be trained using a variety of data sources, while smart contracts would be used to ensure the predictions are accurate and to reward those who made accurate predictions.