Telomere extension, the Hayflick limit: Dendrites and axons with keratins expressed in the human integumentary system

in #communicable-diseases6 years ago (edited)

Is it possible to lengthen telomeres?

Researchers say they have found a way to lengthen human telomeres - the protective caps at the end of chromosomes. ... However, telomeres become shorter with each cell division and can reach a point where they are no longer able protect the chromosomes, leaving them open to deterioration.

Telomerase, also called terminal transferase,is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of eukaryotic chromosomes in most eukaryotes. Telomeres protect the end of the chromosome from DNA damage or from fusion with neighbouring chromosomes. The fruit fly Drosophila melanogaster lacks telomerase, but instead uses retrotransposons to maintain telomeres.

Telomere extension turns back aging clock in cultured human cells, study finds

Telomerase is an enzyme that lengthens telomeres and keeps them from wearing out too fast or too early. But with constant cell division, telomerase levels are depleted, enabling telomeres to shorten. ... Because while telomerase does lengthen telomeres, in humans with cancer, the enzyme helps existing tumors grow faster.

The Hayflick limit or Hayflick phenomenon is the number of times a normal human cell population will divide before cell division stops.

Progress in a Universal Cancer Vaccine

What is the main function of the dendrites?

Dendrites are the segments of the neuron that receive stimulation in order for the cell to become active. They conduct electrical messages to the neuron cell body for the cell to function.

Integumentary system

What is a dendrite and an axon?

Neurons have specialized projections called dendrites and axons. Dendrites bring information to the cell body and axons take information away from the cell body. Information from one neuron flows to another neuron across a synapse. The synapse contains a small gap separating neurons.

“Cousin Jacks”, What's in the CRISPR?

By David Hirsch

Chinese Scientist Claims to Use Crispr to Make First Genetically Edited Babies

The researcher, He Jiankui, offered no evidence or data to back up his assertions. If true, some fear the feat could open the door to “designer babies.”

Ruth Itzhaki, a professor in the Division of Neuroscience and Experimental Psychology at the University of Manchester, U.K., told Newsweek last month that a commonly transmitted herpes virus could be causing 50 percent Alzheimer's disease cases.

Experimental Alzheimer's Disease Vaccine May Cut Dementia Cases In Half

Palliative care is an approach that improves the quality of life of patients and their families facing the problem associated with life-threatening illness, through the prevention and relief of suffering by means of early identification and impeccable assessment and treatment of pain and other problems, physical, psychosocial and spiritual.

Communicable diseases and community living arrangements have complex considerations.

Palliative-pollution pundit Pruitt
By David Hirsch

In a List of target antigens in pemphigoid:

A Herpes Gestation with Antigen NC16A terminal of BPAG2
BPAG1 is mentioned. The experimental Vaccine may be based off of this target antigens as:

keratins expressed in the human integumentary system

As well in research articles mentioned development of strategies and techniques developed by Bonnie Bassler:

How Bacteria Talk to Each Other

SBIR research may be proposed in an interstate teaming agreement to address technology gaps.

Applying for Grants

Considerations from this article include:

Rice University investigates professor's involvement in genomic editing of human embryos

Mark 5:1-20
Jesus Restores a Demon-Possessed Man

After Onan's brother Er died, his father Judah told him to fulfill his duty to his brother by entering into a levirate marriage with his brother's widow Tamar to give her offspring. Religion professor Tikva Frymer-Kensky has pointed out the economic repercussions of a levirate marriage: any son born to Tamar would be deemed the heir of the deceased Er, and able to claim the firstborn's double share of inheritance. However, if Er were childless, or only had daughters, Onan would have inherited as the oldest surviving son. When Onan had sex with Tamar, he withdrew before his orgasm and "spilled his seed [or semen] on the ground", since any child born would not legally be considered his heir.

Homelessness in the United States

"Open the rooms where the winds are locked up and make them blow for me; show me a picture of a sound."

-From the Second Book of Esdra chapter 5

In the Bible, Oholah and Oholibah are mentioned from Ezekiel 23, the sinful sisters: In the Hebrew Bible, Oholah and Oholibah are pejorative personifications given by the prophet Ezekiel to the cities of Samaria in the Kingdom of Israel and Jerusalem in the kingdom of Judah, respectively. They appear in the Book of Ezekiel, chapter 23. There is a pun in these names in the Hebrew.

Hysterical breaking of the Turkey Wishbone in sibling rivalry as pursuits to bury the hatchet

Ezekiel 24 closes with 'The Death of the Prophet's Wife' and Saint Fabiola is the patron saint of difficult marriages, divorced persons, Saint Fabiola was a nurse and Roman matron of rank of the company of noble Roman women who, under the influence of the Church father St. Jerome gave up all earthly pleasures and devoted themselves to the practice of Christian asceticism and charitable work.

Disadvantaged Business Enterprise

Closing considerations meditating upon the Mark 10 verse on Divorce and considered past Saint Fabiola, becoming a saint, Gangulf was an unlucky knight who suspected his wife of infidelity and is the patron saint for deceived husbands are comparison contrast social conventions of Onan and Hagar to some degree. Hagar gave birth to Ishmael from Abraham and Sarah had them sent away to Mecca in Saudi Arabia where Muhammad was born.

Religious restrictions on the consumption of pork

Governance, corruption, and conflict

Friday, 19 August 2016
Hacked Docs Expose Soros-Obama-UN Refugee Invasion Network
Written by William F. Jasper

Al-Yamamah arms deal

According to the Bible, Boaz and Jachin were two copper, brass or bronze pillars which stood on the porch of Solomon's Temple, the first Temple in Jerusalem.

Revealed: Britain's torture of Obama's grandfather
Hussein Onyango Obama, a British soldier in the second world war, was locked up as a Mau Mau rebel in Kenya
By Owen Bowcot

Saudis Said to Use Coercion and Abuse to Seize Billions
The Saudi government locked up hundreds of powerful businessmen and royals in the Ritz-Carlton hotel in Riyadh in what it said was a crackdown on corruption.
By Ben Hubbard, David D. Kirkpatrick, Kate Kelly and Mark Mazzetti

Multiorgan transplants
Xenotransplantation research includes genetic engineering of pigs so that their organs are compatible for transplant to humans. In addition, researchers are looking at treating diseases through transferring genes into tissues (gene therapy).

Khidr or al-Khidr (Arabic also transcribed as al-Khadir, Khader/Khadr, Khidr, Khedher, Khizr, Khizir, Khyzer, Qeezr, Qhezr, Qhizyer, Qhezar, Khizar, Xizir, Hizir) is a name ascribed to a figure in the Quran as a righteous servant of God possessing great wisdom or mystic knowledge. Mystic, Green One, The Verdant One, Teacher of the Prophets "Sayyidina"

Daniel 11:15 The king of the South will become strong, but one of his commanders will become even stronger than he and will rule his own kingdom with great power.

Republicans Senators Who Tried to Kill Yemen War Resolution Were Paid by Saudi Lobbyists
By Cristina Maza

Macron tells Saudi prince international experts needed in Khashoggi investigation

April 17, 2017
Following Super PAC Support, Private Prison Company Wins Trump Admin Contract
By Maya Gold

in August of 2016 -- back when most election polls had Hillary Clinton clinching the 2016 presidential election -- the Obama administration announced that it would end the Justice Department’s (DOJ) reliance on private prisons. The announcement came seven days after the DOJ’s inspector general (IG) called on the federal Bureau of Prisons (BOP) to more rigorously oversee its contracts with private prison companies. The IG’s report found that private prisons at the federal level consistently fail to measure up to federal standards in preventing dangerous conditions, intercepting contraband, and ensuring internal accountability for staff misconduct.

Private prison companies likely to be big beneficiaries of Trump's plan to detain more border-crossers

Obama in ancestral home Kenya to launch sister’s project
By TOM ODULAJuly 15, 2018

Maurice Strong, Climate Crook The consummate sleazebag, thief and all-round corruptocrat who launched and shaped the UN effort to rid the world of CO2 has died, appropriately enough as his heirs gather in Paris to rob the world blind.

Farewell to the man who invented 'climate change’
To this day, global climate policy is still shaped by the agenda of Maurice Strong, a Canadian multimillionaire
By Christopher Booker

An Argentinian Prosecutor Is Investigating Saudi Crown Prince Mohammed bin Salman for Possible Crimes Against Humanity
By Eli Meixler

Year of the Dog and Pony show for bread and circuses

Trump’s First Year Has Been the Private Prison Industry’s Best
The Trump administration has been a godsend for the private prison industry.
By Lauren-Brooke "L.B." Eisen
January 15, 2018

Pork barrel is a metaphor for the appropriation of government spending for localized projects secured solely or primarily to bring money to a representative's district. The usage originated in American English. In election campaigns, the term is used in derogatory fashion to attack opponents.

Jared Kushner pushed to inflate Saudi arms deal to $110 billion: Sources
By Tara Palmeri

Corky's BBQ is slow cooked and hand pulled, it's the best Memphis style BBQ.

Law & the Courts
Religion and the New Supreme Court
By John Yoo
& James C. Phillips

When in Texas, what time should you get in line at Franklin's BBQ?

Franklin doesn't even open until 11:00am, but the line starts forming around 7:00 or 8:00 in the morning. The line grows and grows until the doors open and then moves slowly until they run out of meat. When it's gone, it's gone. The idea of waiting up to four hours for lunch is absurd to some.

Who benefits from pork barrel spending?

While it may help some bills get passed through the legislative process, pork barrel spending is often considered a wasteful use of taxpayer funds because it benefits select constituents of Congressional members rather than the country as a whole.

The China Thread and all things Maurice Strong

Foreign Policy, Intelligence, International, Latin America, Politics, Secrecy
George H.W. Bush, the CIA and a Case of State-Sponsored Terrorism
By Robert Parry

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