I know that - I participated in medical study while I was working in Russia in 2012 - the study wanted to know the effects of Cannabis Juice (the juicing of the plant itself) there was no THC as the fans and buds were not heated to release them and I was given 60 ml's 3 times a day (mixed with better tasting juices of course) and after 3 weeks I had to reduce my diabetic meds and after 6 weeks I was off them completely - I was on the study for 4.5 months (I had to return to Canada for family emergency) and during this time I had lost 18 Kg's - So there is some merit to CBD only - now I was told that the amount of CBD varied with the plants used in juicing - but was told by the clinicians that it would be around 10g /ml so that would be a daily dose of around 1800g, now I have used oil with a 0.2 g/ml THC 20g/ml CBD but have never reached the effects that the juicing of the plant gave me. As for pain relief I've used a similar rub that this company has with excellent results for my neuropathy in my feet, and pain in my knees. High CBD no THC. I'm going to try their products and see what happens - if nothing then I just go back to my expensive medical cannabis from the dispensary - I don't have the patience or desire to grow my own or else I would just duplicate the "juice" part of the study - thing is I don't know what strain they used in the study and unfortunately the doctor in charge of this study was killed in a car accident in 2015