Some do fit more comfortably in larger hands, others in smaller...

Hand size is a function of body size and is usually determined by nutrition, diet and robustness requirements of the environment.

Body shapes and sizes have varied widely throughout the evolutionary family tree, as they do today, where we have 4 ft and less to 7 ft or more individuals.

These are often related to race and geographical distribution today, which is a result of isolation under a certain set of conditions over very long periods.