SEC S20W1 || Hematopoiesis - Module 1

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Am super happy to make an entry into this contest. Well am not a medical student but you know, there's is this common saying that says no knowledge is lost. Hence the reason why I decided to look into the medical aspect of this season's engagement contest.

I am willing to gather every bit of knowledge that would be dished here and of course I have so much expectation. Now to the business of the day. I will be making my entry based on how I understand the topic. I might not be just perfect but kindly bear with me as I learn the ropes in this field.

Anatomy and function of hematopoietic organs

I will love to start by defining Hematopoiesis the way I understand it and then delve into the organs and function of the organs responsible for this process. Alright let's get right into it.

Hematopoiesis is a combination of two greek words, Haîma which simply means blood and Poiēsis which means to create or produce. Combining both meaning together is what gave us the concise definition of the word hematopoiesis.

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freepik

Hematopoiesis simply means the production of blood in the system of a living organism. Our use case for this topic is man. So I will be limiting our discussion of to formation and production of blood in man. This also captures how new blood are created in the body to replace old one.

These blood helps fight against sickness and disease (White blood cell) and also help the body clot when there is wound or injury (platelets) and finally the blood that help supply oxygen (red blood cell).

Hematopoiesis Organ

There are some organs responsible for the production of various types of blood we have in the body, they are;

• yoke sack : Blood formation start right from the yolk sack surrounding the embryo. This is where the blood cell needed for the body begins to take form.

• Liver : The lever is another site where blood production takes place and it begins to operate shortly after the fertilization process and it spans up until the spleen takes over with the job

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• Spleen: The spleen is another area where blood production takes place and research has shown that it starts this operation in the middle of the second month until late into the 7th month.

• Bone Marrow: The bone marrow which can be defined as that sponge-like substance in the bone, takes up this duty fully from the spleen till maturity and even till the death of the man. Kindly note that the bone marrow has been functional right from the second month but not fully

Medullary Hematopoiesis vs Extramedullary Hematopoiesis

In this section, we would be looking at the difference between medullary hematopoiesis and extramedullary hematopoiesis.

To start with I would like to make us understand that the term medullary means bone marrow. Synonym for the "extra" attached to the term can be "without" or "outside" . Having defined these terms, let me now attempt to give an answer to the question.

Medullary hematopoiesis means production of blood in the bone marrow while extramedullary hematopoiesis means production of blood outside the bone marrow.

The major organ for medullary hematopoiesis is the bone marrow while the organs for extramedullary hematopoiesis is the spleen and liver.
The spleen and liver feature in the early stage of blood production while the bone marrow takes off shortly after these organs relent

Make a diagram of Hematopoiesis and explain it in your own words.

I believe our teacher really wants to test our understanding about this particular lesson and has asked us to show a graphical representation of what we understand. Am not into medicine so my knowledge is limited, nevertheless, I came up with something below based on my level of understanding

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The image above clearly show the stages and duration that each hematopoiesis organ use in producing the blood cells in the body. I don't know if I really represented this lesson well graphically but I stand to be corrected.

Clinical Case

And here we are in the clinical section of this task. I want to assume the role of a clinical student and see if I will be able to do justice to it. Let's get right into it guys. Your medical student is here to diagnose the situation...lol.

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In your opinion, what are the reasons for significant blood loss?

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In my layman opinion, since am not a medical student, I would like to answer this question by presenting two possible reason

• The first reason why I feel the blood couldn't stop easily that the man had to loss so much blood is that...he might be low on the blood cell called platelets which help with blood clotting. When there is an injury, the platelets tries to put an end to it by causing it to clot but when the body system lacks it, an injured person is likely to lose so much blood.

• The second reason for the huge loss of blood was from the broken femur. The Femur is one of the important bone in the body system of the man located in the leg region of a man.

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We have learnt in this lesson that from 7month to maturity, the bone marrow produces most of the blood tissue needed by the body, especially the red blood cell. There was so much loss of blood because one of the production house (Femur) got broken.

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Who would be the ideal person to donate blood to? (ideal donor profile)

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According to my limited knowledge about blood donation, I know the blood sample of the victim would first be collected and tested. The goal of this test is to know what kind of blood they would be needing for that patient.

So the ideal person who should donate blood to that fellow should be someone who has a blood that matches the blood of the victim and in my humble opinion, the donor should also be someone who has more than enough white blood cell to complement the blood cells the patient already has.

Conclusion

Finally I get to drop my pen. I must confess, I learnt a whole lot from this lesson as I personally had to do some mini research to partake in this contest..what a diligent way to learnt. Anyway I'm looking forward to a favourable response from our teachers.
I would love to invite @ruthjoe @mostofajaman @ninapenda to this contest. I hope they find it interesting.

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Regards
@lhorgic❤️

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